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Name:Anefrin Nasaloriginal
Manufacturer:Walgreen Company
Category:Over-the-counter (OTC) Marketed Drugs

Walgreens Co. Anefrin Nasal Spray Drug Facts

ANEFRIN NASAL ORIGINAL - oxymetazoline hydrochloride spray 
Walgreen Company

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.


Walgreens Co. Anefrin Nasal Spray Drug Facts

Active ingredient

Oxymetazoline hydrochloride 0.05%


Nasal decongestant


  • temporarily relieves nasal congestion due to:
  • common cold
  • hay fever
  • upper respiratory allergies
  • shrinks swollen nasal membranes so you can breathe more freely


Ask a doctor before use if you have

  • heart disease
  • high blood pressure
  • diabetes
  • thyroid disease
  • trouble urinating due to an enlarged prostate gland

When using this product

  • do not use more than directed
  • do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen.
  • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur
  • use of this container by more than one person may spread infection

Stop use and ask a doctor if

symptoms persist

If pregnant or breast-feeding,

ask a health professional before use.

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.


  • adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period.
  • children under 6 years of age: ask a doctor

To spray, squeeze bottle quickly and firmly. Do not tilt head backward while spraying. Wipe nozzle clean after use.

Other information

  • store at 20°-25°C (68°-77°F)
  • retain carton for future reference on full labeling

Inactive ingredients

benzalkonium chloride solution, benzyl alcohol, edetate disodium, polyethylene glycol, povidone, propylene glycol, purified water, sodium phosphate dibasic, sodium phosphate monobasic



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Compare to Afrin® Original active ingredient


Anefrin Nasal Spray

Oxymetazoline HCl 0.05%

Nasal Decongestant


12 Hour Relief

Clears Stuffy Noses Fast

Soothes as it relieves

Anefrin Nasal Spray Carton

Anefrin Nasal Spray Carton

oxymetazoline hydrochloride spray
Product Information
Product Type HUMAN OTC DRUG Item Code (Source) NDC:0363-0304
Route of Administration NASAL DEA Schedule     
Active Ingredient/Active Moiety
Ingredient Name Basis of Strength Strength
Product Characteristics
Color WHITE (Translucent) Score     
Shape Size
Flavor Imprint Code
# Item Code Package Description Multilevel Packaging
1 NDC:0363-0304-10 1 BOTTLE, SPRAY ( BOTTLE) in 1 CARTON contains a BOTTLE, SPRAY
1 30 mL in 1 BOTTLE, SPRAY This package is contained within the CARTON (0363-0304-10)

Marketing Information
Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date
OTC monograph final part341 09/28/1995

Labeler - Walgreen Company (008965063)

Revised: 11/2009 Walgreen Company

Reproduced with permission of U.S. National Library of Medicine

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